Faculty & Staff

· Abdel Aziz Shaheen
· Bertus Eksteen
· Carla Coffin
· Cathy Lu
· Chris N. Andrews
· Christian Turbide
· Cynthia H. Seow
· Eldon Shaffer
· Gil Kaplan
· Humberto Jijon
· Joan Heatherington
· Jon Meddings
· Jonathan Love
· Jose G.P. Ferraz
· Kelly Burak
· Kerri Novak
· Lawrence Price
· Maitreyi Raman
· Marie-Louise Martin
· Mark Swain
· Meredith Borman
· Paul James Belletrutti
· Paul L. Beck
· Puja Kumar
· Remo Panaccione
· Ronald Bridges
· Samuel Lee
· Stephen Congly
· Yasmin Nasser

Foothills Medical Centre

Paul L. Beck, MD, PhD, FRCPC

Professor of Medicine
Faculty of Medicine, University of Calgary

Administration Office:
Phone: 403-592-5025  Fax: 403-592-5025

Clinic:
Phone: 403-944-6516  Fax: 403-944-6548
 

Curriculum Vitae

Queen's University, BSc (Hons), Queen's University, Kingston, Ontario, Canada PhD, Biology, University of Calgary, Calgary, Alberta, Canada - MD Harvard University General Hospital, Boston, Massachusetts, United States - Post-Doctoral Studies, Post-Doctoral Research Fellowship in Gastroenterology and Molecular Biology University of Calgary, Calgary, Alberta, Canada - Gastroenterology, Fellowship in Gastroenterology. University of Calgary, Calgary, Alberta, Canada - Residency in Internal Medicine, Internal Medicine, Residency in Internal Medicine. Calgary General Hospital, Calgary, Alberta, Canada - Rotating Internship, Medicine.

 

Clinical/Research Interests

Dr. Beck's research interests include defining mechanisms involved in the development of IBD and how the gastrointestinal tract heals itself after injury. The lining of the gastrointestinal is commonly injured in everyday life by insults such as arthritis medications, bacteria, viruses' acid and others. Why this injury occurs more commonly in some and causes more problems is unclear, however, it appears that some people are susceptible to injury where others fail to heal the injury and likely IBD is a result of increased susceptibility to injury and failure to properly heal following injury. By using both animal models of colitis as well as tissue culture models the goal of his research is to determine import factors that protect the gastrointestinal tract from injury and/or improve tissue repair after injury. By determining which factors may be involved in these processes one can develop strategies aimed at treating IBD with the ultimate goal of finding a cure for this group of devastating diseases. Dr. Beck's lab is also interested in Clostridium difficile colitis and the pathways involved in causing damage and how the gut protects against it.

 

Publications

Hirota SA, Fines K, Ng J, Traboulsi D, Lee J, Ihara E, Li Y, Willmore WG, Chung D, Scully MM, Louie T, Medlicott S, Lejeune M, Chadee K, Armstrong G, Colgan SP, Muruve DA, Macdonald JA, Beck PL. Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal Injury. Gastroenterology. 2010 Jul;139(1):259-69.e3. Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, Schenck LP, Vilaysane A, Seamone ME, Feng H, Armstrong GD, Tschopp J, Macdonald JA, Muruve DA, Beck PL. Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology. 2010 Aug;139(2):542-52, 552.e1-3. Braedon McDonald, Keir Pittman, Gustavo B Menezes, Simon A Hirota, Ingrid Slaba, Christopher CM Waterhouse, Paul L Beck, Daniel A Muruve, and Paul Kubes. Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation. Science. 2010 Oct 15;330(6002):362-6

Giving
Patient Resources

Referring Physicians